Herbal Plant Extracts

Gynostemma Pentaphyllum Health & Beauty Benefits

Gynostemma Pentaphyllum

Gynostemma pentaphyllum extract is more than 50 kinds of gypenosides isolated from this plant. Like ginsenosides, they belong to the tetracyclic triterpene masaponins. Gynostemma Pentaphyllum has many benefits in health and beauty.

Such as strengthening the body, strengthening physical fitness, activating cells, anti-fatigue, anti-ulcer, anti-aging, lowering blood pressure, lowering blood fat, anti-cancer, strengthening brain and calming nerves, improving liver function, curing hair loss, moisturizing skin, beauty and weight loss. Gynostemma Pentaphyllum has the functions of ginseng, but it does not have side effects of ginseng overdose.

Here is about the role of Gynostemma pentaphyllum in antioxidant, weight loss, and skin & hair care.

Gynostemma Pentaphyllum benefits in Inhibit obesity and regulate fat metabolism

The total saponins of Gynostemma Pentaphyllum and its hydrophilic and effective parts have a variety of physiological activities, combined with excess fat in the human body, have the effect of significantly reducing serum cholesterol, triglycerides and low-density lipoprotein. It can also significantly increase the anti-atherosclerotic substance-high-density lipoprotein. This can regulate fat metabolism and inhibit the decomposition of fat by adrenocorticotropic hormone and the function of converting glucose into fat. It has a significant effect on the prevention and treatment of atherosclerosis and immunocompromised disease.

Gynostemma extract can inhibit the proliferation of more than 20 kinds of cancer cells. The effect can reach 20% to 80%.

The effect of Gynostemma pentaphyllum in reducing blood lipids and inhibiting obesity is related to its inhibition of fat cells to produce free fatty acids and synthesis of neutral fat. Gypenosides have unique advantages in practical performance. Gypenosides regulate the body’s fat metabolism and inhibit the conversion of glucose to fat, significantly reduce weight and reduce the thickness of subcutaneous fat. It can also regulate the vasoconstriction and diastolic properties and improve blood circulation. It is good for preventing obesity.

Effect on blood sugar
The influence of Gynostemma pentaphyllum on sugar metabolism has attracted people’s attention. Research results show that Gynostemma pentaphyllum can prevent diabetes in the elderly. Clinical application of Gynostemma pentaphyllum to prevent and treat senile diabetes has achieved certain results, which is related to the hypoglycemic effect of Gypenosides and the improvement of glucose tolerance.

Gynostemma Pentaphyllum benefits in anti-aging and anti-oxidant

Activation of cells
Gynostemma pentaphyllum prolongs the number of generations of the cells that make up the organism. When the total glycosides is 200 mg/L in the culture medium, the human fetal normal diploid fibroblasts (WI-1) multiply to 59 generations. In the control group, the growth stopped at only 51 generations, and the growth was extended by 15.7%. In vitro culture of the skin cells of patients with Werner’s syndrome, the control group only reproduced for 22 generations, and the Gynostemma pentaphyllum group was extended to 27 generations, which was 22.7%.

Cell passage tests show that Gynostemma pentaphyllum has the effect of prolonging the lifespan of cells. The lifespan of organisms (including the human body) depends on the lifespan of cells, the most basic unit of organisms. Therefore, Gynostemma is analyzed from the perspective of prolonging cell life, and it also has the effect of extending life.

A large number of experiments show that Gynostemma pentaphyllum has the effect of anti-aging and prolonging life. The mechanism is achieved through anti-oxidation and prolonged cell reproduction and passage.

Lipid peroxide (LPO) in the body can cause changes in biofilms with high lipid content, damage the structure of cell ribonucleic acid (RNA) and deoxyribonucleic acid (DNA), cause protein molecules to cross-link, and lead to cells Aging, tissue damage and lipofuscin precipitation, etc.

Elimination or reduction of LPO is the prerequisite for maintaining the body’s normal and vigorous metabolism. Gynostemma pentaphyllum can significantly reduce the content of LPO in the body. Superoxide dismutase (SOD) is a scavenger of superoxide radicals in the body and can reduce the formation of LPO. Gynostemma strongly strengthens SOD activity.

Adding 4% water extract to the feed to feed 5-month-old mice for 2 months increased the SOD activity from 21.69±3.08 units in the control group to 33.5±2.90 units. When other animals in the same batch continued to feed until 4 months, all the animals in the control group died, while 50% of the animals in the Gynostemma pentaphyllum group still survived.

It shows that gypenosides can enhance the activity of SOD, degrade LPO, and activate the special structure of the cell itself and its various protective systems. For example, antioxidant enzymes can prevent or interrupt lipid peroxidation to a certain extent. The anti-oxidant effect achieves the purpose of anti-aging.

Gynostemma Pentaphyllum benefits in Skin Care

Because of cosmetic effect, eating gypenosides can make the skin moisturized and elastic. It may be because Gynostemma saponins participate in cell activation, activate metabolism, strengthen blood circulation, and discharge lipids.

Traditional Chinese medicine believes that Gynostemma pentaphyllum has a bitter taste and cold nature, and has the functions of clearing away heat, detoxifying, relieving cough, and eliminating phlegm. It has a broad-spectrum anti-cancer effect.

Gynostemma pentaphyllum improve the hair microcirculation. This makes the epidermal germinal layer cell metabolism vigorously and strengthen the skin collagen fiber renewal. Thereby it can prevent and treat premature hair graying and senile alopecia.

Gynostemma pentaphyllum can inhibit cell senescence and prolong cell life. The accumulation of scalp cell death forms dandruff. The anti-degeneration and aging effect of Gypenosides can prolong the life of scalp cells. It can also reduce the production of dandruff, and have the functions of sterilizing and antipruritic.

Benefits in Hair Care

Elderly patients with gastric ulcer took gypenoside and found that the ulcer symptoms improved. The gray hair becomes black. The gray hair rate was originally 25% to 80%, and only about 5% of gray hair remained in those with the best effect after treatment.

Using Gynostemma as tea for a long time has a significant effect on gray hair and black hair. According to research, daily use of Gynostemma pentaphyllum (dry product) 0.1 ~ 9.0 grams can reduce gray hair or let gray hair disappeared after 3 months.

The same effect can be obtained by applying the Gynostemma extract to the affected area with water or alcohol. Some people use 20 mg each of gypenosides and soyasaponins, dissolved in black tea and other beverages, and take it every day. After a few months, the hair loss decreased significantly and the hair grew again.

One of the reasons why Gynostemma can cure gray hair is related to its function of improving scalp microvascular channels, promoting lipid discharge, and improving and restoring cell vitality. Gynostemma has a similar effect to vitamin E. The tensile force of the hair treated with Gynostemma pentaphyllum was significantly stronger than that of the blank control water-treated hair, and the hair tenacity was enhanced.

Gynostemma can resist UV damage and nourish hair. Thus, it can prevent the hair from turning yellow and rough due to wind and sun. It is beneficial to the repair of hair damage caused by perm, cold perm, and hair dyeing. As a result, it can make the hair shiny, fluffy and soft.

Gynostemma extract is now available on the market as a hair protectant. For example, 1000 ml of hair tonic contains 5 mg of gypenoside.


Gynostemma pentaphyllum extract is natural plant extract with multiple funtions in health and beauty. Although it is natural and safe, please consult a doctor before use.

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